Which therapy is primarily preventive, requiring injections at regular intervals?

Prepare for the Pharmacology IV – Headache Therapeutics Test. Review the therapeutic approaches, tackle multiple-choice questions with explanations, and boost your test-taking confidence. Ace your exam with precision!

Multiple Choice

Which therapy is primarily preventive, requiring injections at regular intervals?

Preventive migraine therapy delivered by injections at regular intervals is the class of CGRP monoclonal antibodies. These biologics block CGRP signaling (either the CGRP ligand or its receptor), which reduces the frequency of migraine attacks over time. They are given by subcutaneous injections on a regular schedule—monthly or every few months depending on the specific agent (for example, monthly for some, quarterly for others). This distinguishes them from Lasmiditan, which treats acute migraines and is taken as needed (oral), and from gepants, which are also used for acute treatment and taken orally. Triptans are likewise acute therapies. So the option describing CGRP monoclonal antibodies as preventive injections at regular intervals best fits the scenario.

Preventive migraine therapy delivered by injections at regular intervals is the class of CGRP monoclonal antibodies. These biologics block CGRP signaling (either the CGRP ligand or its receptor), which reduces the frequency of migraine attacks over time. They are given by subcutaneous injections on a regular schedule—monthly or every few months depending on the specific agent (for example, monthly for some, quarterly for others). This distinguishes them from Lasmiditan, which treats acute migraines and is taken as needed (oral), and from gepants, which are also used for acute treatment and taken orally. Triptans are likewise acute therapies. So the option describing CGRP monoclonal antibodies as preventive injections at regular intervals best fits the scenario.

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