Which statement about migraine treatment in pregnancy is accurate?

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Multiple Choice

Which statement about migraine treatment in pregnancy is accurate?

In pregnancy, choosing migraine treatment hinges on safety data for the fetus, so therapies with limited human data are approached with caution. CGRP-targeted therapies (the CGRP antagonists) have only sparse data in pregnant people, so they are not considered safe to rely on during pregnancy. Because we lack robust safety assurance, these medications are generally avoided unless there are no better options and the potential benefits justify the uncertain risks. In contrast, acetaminophen is commonly used and considered safe for treating mild to moderate pain in pregnancy, and triptans like sumatriptan have reassuring safety data and can be used if needed; they are not categorically contraindicated. Therefore, the statement that CGRP antagonists are not safe due to limited data is the most accurate choice.

In pregnancy, choosing migraine treatment hinges on safety data for the fetus, so therapies with limited human data are approached with caution. CGRP-targeted therapies (the CGRP antagonists) have only sparse data in pregnant people, so they are not considered safe to rely on during pregnancy. Because we lack robust safety assurance, these medications are generally avoided unless there are no better options and the potential benefits justify the uncertain risks. In contrast, acetaminophen is commonly used and considered safe for treating mild to moderate pain in pregnancy, and triptans like sumatriptan have reassuring safety data and can be used if needed; they are not categorically contraindicated. Therefore, the statement that CGRP antagonists are not safe due to limited data is the most accurate choice.

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