Which neuromodulation devices are approved for patients aged 12 and older?

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The main idea is that not all neuromodulation devices have the same age approvals, so only certain ones are labeled for use in younger patients. Among commonly used migraine neuromodulation options, three have approvals for patients aged 12 and older: single-pulse transcranial magnetic stimulation delivers brief magnetic pulses to the cortex to interrupt the migraine process; external trigeminal nerve stimulation provides mild electrical stimulation to pathways involved in migraine via a forehead-type device; and remote electrical neuromodulation uses a wearable patch to stimulate nerve circuits linked to pain modulation. These devices have pediatric or adolescent data supporting safety and effectiveness, which is why they are approved for 12-year-olds and up. In contrast, non-invasive vagus nerve stimulation devices have approvals that are typically for adults or older adolescents, depending on the labeling, and thus aren’t listed as approved for the 12-and-older category in this context.